Feedback from a Software On Sailboats customer on running Desktop Sales Manager under Windows 7:
1) Upgrade from Windows Home Premium to Ultimate because Home doesn't have Windows XP Mode. Both Windows Pro and Ultimate have XP Mode included for free.
2) Download and install Windows XP Mode and Virtual Machine from Microsoft
3) Download DSM 126.96.36.199 from this site and install
4) You'll be asked to install .Net framework during DSM twice (once for 1.1 and then a service pack)
5) Restart XP Mode, then you are ready to go. Appears to run just fine.